Polyxeni Hotel is located in Samos''s Pythagorio neighborhood, close to Glicorisa Beach, Folklore Museum of Samos, and Agia Triada Monastery. Additional area points of interest include Natural History Museum of the Aegean and Heraion of Samos. Hotel Features. Polyxeni Hotel features multilingual staff and tour/ticket assistance. A bar/lounge is open for drinks. Guestrooms. 21 air conditioned guestrooms at Polyxeni Hotel feature hair dryers. Guestrooms offer phones.