This region is also famous for its nature and architecture. It also hosts the original family home of Fidel Castro at Finca La Mancas in Biran. It is all very low key, but if you are interested in the home life of the revolutionary leader you can explore.
Getting out of the resort also gives you a chance to see ordinary Cuban life at first hand in this very rural area. Don't be surprised to see lots of people waiting along roads, a formalised kind of hitch-hiking operates on the island, so everyone stops and gives others a lift.
West of Guardalavaca is Gibara where you can visit an impressive memorial commemorating Christopher Columbus's visit to Cuba. Stop for lunch at the restaurant here and find out more about the famous explorer on one of the tours.
For cyclists and keen walkers there are lots of trips in this area where you can explore country roads and coastal paths near to the resort, which lead you into hidden coves and to almost-secret beaches.
You shouldn't miss out on a trip to Havana during your holiday in Cuba. It is possible in a day if you take an internal flight from Holguin, although it might be more fun to stay overnight. Havana's combination of history, atmosphere and great cocktail bars make it top of the list of must-see places on the island.
The tourist trail revels in the influence of American writer Ernest Hemingway of the 1920s and 1930s when Cuba was a playground for rich Americans. The Hemingway touch can be found in bars (where he drank), hotels (where he stayed) and places that he just might have passed.
Take a trip in the funny egg-shaped taxis that run through the centre of the city, wander through the impressive historic quarter with its interesting shops and cafes, and stop for a fantastic mojito at the impossibly grand Hotel Nacional. Like the rest of Cuba, Havana is still very affordable for British tourists.